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Fig. 3 | Retrovirology

Fig. 3

From: Combination of nanoparticle-based therapeutic vaccination and transient ablation of regulatory T cells enhances anti-viral immunity during chronic retroviral infection

Fig. 3

Combinational therapy of regulatory T cell depletion and vaccination with functionalized CaP nanoparticles strongly enhances retroviral clearance. Chronically FV-infected DEREG mice were vaccinated as described in Fig. 2. 7 d.p.v., mice were sacrificed, and infectious centers in the spleen were determined. Results of four independent experiments were combined. Bars represent mean ± SEM. One-way ANOVA followed by Bonferoni’s multiple comparison test was performed to analyze statistics of multiple group sets. *p < 0.05

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Retrovirology

ISSN: 1742-4690

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